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In our articles you can learn more about Disease And Treatment including sign and symptom, laboratory testing, diagnosis, prognosis, diet. We provide you many of serious medical cases from acute to chronic disease, health guides, medical reports, advice & support for the patient







Renal Failure or Kidney Failure Disease

Renal failure or kidney failure also called as renal insufficiency is describes a medical condition in which loss of your kidneys' ability to perform their main function of eliminating excess fluid and salts (electrolytes) as well as waste material from your blood.

Renal failure disease is typically detected by an elevated serum creatinine level in laboratory test result. Problems frequently encountered in kidney malfunction include abnormal fluid levels in the body, abnormal levels of potassium, phosphate, calcium, deranged acid levels, and (in the longer term) anemia as well as delayed healing in broken bones.


- Classification of Renal Failure Disease ;

There are two forms of renal failure ; acute {acute kidney injury (AKI) or acute renal failure (ARF)} and chronic {chronic kidney disease (CKD) or chronic renal failure (CRF)}. Other factors which may help differentiate acute renal failure from chronic renal failure include anemia and the kidney size on ultrasound examination. Chronic renal failure generally leads to anemia and small size of kidney.


- Sign and Symptom of Renal Failure Disease ;

In every patient those diagnose as renal failure usually has different symptom, It can vary from person to person. Symptoms of acute renal failure may include:
  • Nausea and vomiting.
  • Pain in the back just below the rib cage. This is called flank pain.
  • Little or no urine when you urinate.
  • Not feeling like eating.
  • Swelling, especially in your legs and feet.
  • Feeling confused, anxious and restless, or sleepy.
Sometimes acute renal failure causes no signs or symptoms and is detected through laboratory tests done for another reason. Symptoms of chronic renal failure are include:

Chronic renal failure (CRF) symptoms is measured by renal function test as the glomerular filtration rate (GFR), where the result falls below 30 milliliters per minute (< 30 mL/min) signs of uremia (high blood level of protein by-products, such as urea) may become noticeable. When the GFR falls below 15 mL/min most people become increasingly symptomatic. Chronic renal failure can be present for many years before you notice any symptoms.

Some of the symptoms such as fatigue have been present for some patient. If your doctor suspected your self as renal failure case, you need to regular monitoring of your blood and urine test. Otherwise the symptoms may not be detected until the kidneys have already been damaged. Signs of chronic renal failure obvious than others are:
  • decreased urination
  • increased urination, especially at night
  • urine that is cloudy or tea-coloured
  • blood in the urine (not a common symptom of chronic renal failure)
When the kidneys' inability to eliminate waste and excess fluid from the body, symptom will appear as below:
  • thirst
  • fatigue
  • weight loss
  • a yellowish-brown tint to the skin
  • shortness of breath
  • loss of appetite
  • nausea and vomiting (this is a common symptom)
  • puffy eyes, hands, and feet (called edema)
  • high blood pressure
  • bad taste in the mouth or bad breath
  • generalized, persistent itchy skin
  • muscle twitching or cramping
The results of laboratory tests may change suddenly (within a few days to 2 weeks). Such as tests BUN, Creatinine clearance, Serum creatinine, Serum potassium and Urinalysis.


- Causes of Renal Failure Disease ;

  • Acute renal failure, usually occurs when the blood supply to the kidneys is suddenly interrupted or when the kidneys become overloaded with toxins. Heavy blood loss, an injury, or a bad infection called sepsis can reduce blood flow to the kidneys. Including when some one loss to much water (diarrhea) and become dehydration. Also complications from surgeries in which the kidneys are deprived of normal blood flow for extended periods of time.

    Drug overdoses, accidental or from chemical overloads of drugs such as antibiotics or chemotherapeutics, may also cause the onset of acute kidney failure. Examples of medicines that can sometimes harm the kidneys include:
    - The dyes used in some X-ray tests.
    - Antibiotics, such as gentamicin and streptomycin.
    - Some blood pressure medicines, such as ACE inhibitors.
    - Pain medicines, such as aspirin and ibuprofen.


  • Chronic renal failure, The most common is diabetes mellitus. The second one is long-standing, uncontrolled of hypertension or high blood pressure. The third one is chronic glomerulonephritis. The other common causes of CRF are polycystic kidney disease, reflux nephropathy, kidney stones, and prostate disease. Some infectious diseases such as hantavirus can attack the kidneys, causing kidney failure.


  • - Treatment of Renal Failure Disease ;

    Treatment of renal failure can vary widely, depending on the cause and sign or symptom that appear by test lab or other examination. Once the cause is found, the goal of treatment is to restore kidney function and prevent fluid and waste from building up in the body while the kidneys heal. Dialysis may be needed, and can make the patient feel better.

    For example the doctor may restore blood flow to the kidneys, stop any medicines that may be causing the problem, or remove or bypass a blockage in the urinary tract. Some medication are giving to the patient with real failure disease such as calcium, glucose or sodium polystyrene sulfonate (Kayexalate) to prevent the accumulation of high levels of potassium in the blood. More potassium in the blood can cause dangerous irregular heartbeats (arrhythmias).

    Antibiotic usually prescribe to prevent or treat infections. in order to help and support the medication, doctor will suggest the patient with renal failure disease to take diet high in carbohydrates and low in protein, salt, and potassium.


    Disease and Treatment @ 3:29 PM,

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